Liver palms are pathologic changes of redness in the palms of the hands that can occur in patients with chronic liver disease, and are commonly found in people with acute or chronic hepatitis or cirrhosis of the liver. In the clinical physical examination, it can be found that some people have red plaques on the palms of their hands at the big and small fiducial margins and fingertips, or the palms of their hands at the big and small fiducial margins are often red and the color can be faded after applying pressure, and the laboratory examination mostly suggests that there is liver dysfunction, and clinically this pathological change in the palms of the hands is called the liver palms. The appearance of liver palms is related to the weakened inactivation of estrogen by the liver. The liver is an important metabolic organ. In patients with acute or chronic hepatitis or cirrhosis, liver cells are destroyed, normal physiological functions are affected, and the inactivation of estrogen is weakened, leading to the emergence of liver palms and spider nevi. If you suspect that you have abnormal symptoms such as liver palms, you should go to the hospital in time to check whether there are any liver lesions and treat them under the guidance of your physician.