Vomiting and diarrhea after drinking alcohol are considered to be characteristics of acute gastroenteritis after drinking alcohol. First of all, pay attention to rest and drink sugar water appropriately. Sugar water has the effect of absorbing alcohol, hydrating and preventing water-electrolyte disorders. Next, give symptomatic treatment with drugs, commonly used are oral rehydration salts, potassium chloride extended-release tablets and rabeprazole capsules, bifidobacteria capsules, gastroparesis granules and other symptomatic treatment. If oral medications are not seen to relieve, it is also necessary to give montelukast, or loperamide hydrochloride capsules orally, intravenous fluid infusion, pantoprazole injection intravenously, or vitamin C, potassium chloride intravenously, to replenish effective water electrolytes. It is also necessary to improve the blood routine and ion analysis to clarify the situation of blood potassium and blood sodium. If there is hypokalemia or hyponatremia, potassium and sodium supplementation is also needed.