What is the most accurate test for myeloma?

Bone marrow aspiration is the most accurate test to confirm the diagnosis of myeloma, which is confirmed by a bone marrow aspiration biopsy that reveals a large number of abnormal plasma cells.
Myeloma is a malignant tumor originating from plasma cells in the bone marrow, and is mainly manifested by persistent spinal or back pain that progressively worsens. There is usually progressive anemia with markedly increased blood sedimentation. Common tests include imaging tests, general laboratory tests, etc. If a large number of abnormal plasma cells are found during bone marrow aspiration biopsy, the diagnosis of myeloma can be confirmed.
Bone marrow aspiration is often chosen from posterior superior iliac spine or anterior superior iliac spine, which has clear bony markings, no large blood vessels and nerve trunks around, and is safer. If repeated puncture is unsatisfactory, sternal puncture can be chosen in a few cases.
Once persistent pain occurs, you should go to the hematology department of regular hospitals in time to find out the cause and get treatment under the guidance of doctors.