The injection site of rabies immunoglobulin is mainly the localized skin tissue of the bite wound. According to the guidelines of the Expert Consensus on Rabies Exposure Prevention and Handling, rabies immunoglobulin injection is a passive immunization method, and it is recommended that local infiltration injections be given directly around the skin tissues of the bite wounds, and saline can be used to dilute the injection appropriately if necessary. When injecting locally, wounds such as fingers and nose tips are not fully utilized due to anatomical and physiological problems, and it is not recommended that the remaining preparation be injected intramuscularly away from the wound for inoculation. Rabies is a lethal disease. For bites and exposed wounds caused by canine animals, proper treatment should be sought from a physician as soon as possible, with timely and effective debridement and, if necessary, injection of rabies vaccine for active immunization and/or rabies immunoglobulin for passive immunization to avoid serious consequences.