Does the Chinese herb rhubarb have any effects and dangers?

The Chinese medicine rhubarb is used to treat blood-heat epistaxis (vomiting of blood and nosebleeds due to blood-heat) and constipation due to solid heat. Overdose of rhubarb may lead to poisoning, especially fresh rhubarb is more toxic.
Rhubarb is cold in nature, bitter in taste, and belongs to the spleen, stomach, large intestine, liver and pericardium meridians. The effects of this product are diarrhea and attacking accumulation, clearing heat and fire, cooling the blood and removing toxins, expelling blood stasis and clearing the channels (removing blood stasis and clearing the channels), inducing diuresis and eliminating jaundice (eliminating dampness and eliminating jaundice).
It is used in treating constipation due to solid heat, epistaxis due to blood-heat, redness of the eyes and swelling of the throat, carbuncle, carbuncle and abdominal pain (pain in the right side of the abdomen caused by carbuncle in the intestines and viscera), menstrual stasis, postpartum stasis, bruises, dysentery due to dampness-heat, jaundice, gonorrhea, edema, etc. It is also used in treating burns externally.
Caution should be exercised in pregnant women, before and after menstruation and during lactation, and in those with cold spleen and stomach. Overdose of rhubarb may lead to poisoning, especially fresh rhubarb is more toxic, can cause nausea, vomiting, dizziness, abdominal distension and pain, jaundice and so on.
Drugs should be taken under the guidance of a physician, do not self-medication, to avoid causing adverse consequences.