Whether a perianal abscess can be treated through a combination of injections, medications, and topical medications is related to one’s own physical fitness and the degree of infection of the disease. In general, a mild perianal abscess can be improved or controlled by a combination of injections, medications and topical medications, but surgery is recommended for severe cases. 1. Minor perianal abscess: the infection is not serious, the symptoms are not obvious, the local perianal abscess did not form pus, so you can through the injection, medication systemic treatment, such as oral or static cefepime, amoxicillin or metronidazole and other antibiotics, to give anti-infective treatment, supplemented with topical application of drugs, such as mupirocin ointment, etc. The treatment played a role in certain effects, the condition can be controlled and improved. 2. Severe perianal abscess: If the perianal abscess has localized liquefaction and abscess formation, and the effect of injection, medication, topical application of drugs is not good, swelling, pain, fever and other symptoms are not relieved, then it is recommended that the perianal abscess be incised through surgery, drainage, decompression, and then change the medication to the inner layer of the tissues to heal slowly. The treatment of perianal abscess, once diagnosed, through the professional doctor’s diagnosis, according to the specific conditions, follow the doctor’s advice to choose the best treatment plan, do not self-medication, so as not to delay the condition.