Clinically there is no elderly night urination how to cure the most effective statement, the phenomenon may be too much water before going to bed, the elderly bladder function decline and other physiological factors, generally do not need special treatment. The next consideration is prostate hyperplasia, diabetes and other diseases, patients can take medication, surgical treatment. 1. Physiological factors: the elderly due to the decline in the function of many organs, often appear bladder urinary storage function decline and so on, will lead to the elderly night urination frequently. Secondly, if the elderly drink too much water before going to bed, the situation of frequent nocturia can also occur. This phenomenon generally do not need special treatment, pay attention to drink less water before going to bed. 2. Prostatic hyperplasia: usually patients need to follow the doctor’s instructions to use doxazosin, tamsulosin and other alpha-blockers, and also need to use finasteride, dutasteride and other 5 alpha-reductase inhibitors. Some patients may also be treated with M receptor antagonists such as tolterodine and oxybutynin. If the patient’s condition is serious, affecting the treatment of life, or drug treatment is ineffective, it may be necessary to carry out transurethral resection of the prostate, transurethral laser surgery under the guidance of the doctor. 3. Diabetes: Usually patients need to follow the doctor’s instructions oral glibenclamide, metformin, reglanatide and other hypoglycemic drugs treatment, can promote insulin secretion. Patients can also inject insulin or glucagon-like peptide-1 receptor agonist, can play a sugar-lowering effect. Clinical causes of nocturnal enuresis in the elderly are many, it is recommended that the patient first consult a doctor for examination, to clarify the cause of the disease and then carry out the appropriate treatment, the drug should be applied under the guidance of a doctor.