Whether children take cephalosporins or azithromycin is related to the type of pathogenic bacteria, cephalosporins are suitable for bacterial infectious diseases, and azithromycin is suitable for infectious diseases such as Haemophilus influenzae and Mycoplasma. It is necessary to use the appropriate drug according to the condition and under the guidance of the doctor. Cephalosporins are used clinically to treat diseases caused by Staphylococcus aureus, Streptococcus pneumoniae and other sensitive bacterial infections. Azithromycin belongs to the class of antibiotics of macrolides, which is used to treat infectious diseases such as Haemophilus influenzae, Catamorpha, Streptococcus pneumoniae, Mycoplasma and other infectious diseases in the clinic. Due to individual differences, the drug does not exist absolute effective and safe, it is recommended to strictly follow the doctor’s instructions to use, do not recommend unauthorized use. Adverse reactions are recommended to seek medical attention, drug allergy is prohibited, cephalosporins are prohibited to drink alcohol during the use of the drug.