If you experience dry skin after applying Acyclovir Cream, you may apply a moisturizer to relieve the symptoms. Acyclovir cream is a topical antiviral drug that inhibits herpes simplex virus, varicella zoster virus, etc. It is usually used to treat herpes simplex or herpes zoster infections, and mild pain, burning, stinging, itching, and rashes may occur after use, as well as local dryness in some people, and the symptoms are not serious, and the medication can usually be continued, and moisturizers can be applied to alleviate the dryness and discomfort. Acyclovir cream use in the process of burning sensation, itching, redness, swelling and other situations should be discontinued, and wash the local drug, timely hospital treatment, under the guidance of the physician to replace the drug.