It is also of certain significance to treat colon cancer in the late stage. Colon cancer, a malignant tumor disease, has shown a rising trend in morbidity and mortality in China, and its exact cause is not clear, which may be related to heredity, diet, environment and other factors. In the advanced stage of colon cancer, although the possibility of complete cure is basically lost, and the malignant tumor in the body has spread and metastasized, patients still need to choose a combination of chemotherapy according to the actual condition and physical strength score of the individual, and in the case that conventional treatment is not applicable, local treatment and supportive treatment can also be used to improve clinical symptoms and improve the quality of life. In conclusion, colon cancer patients still need to receive standardized treatment even if the disease has progressed to the advanced stage.