The differentiation between ascites and obesity is mainly manifested in the following points: First, in terms of pathogenesis, ascites is mainly a clinical disease caused by the lack of albumin synthesis in the body for various reasons, which leads to an increase in abdominal leakage fluid. Obesity is caused by excess nutrition, resulting in the deposition of subcutaneous fat. Second, from the point of view of clinical manifestations, ascites is mainly manifested as abdominal expansion, especially when the serious ascites can be manifested as frog-like abdomen, but the limbs will appear wasted or even cachexia state. Obesity, on the other hand, is not only abdominal swelling, while the limbs and subcutaneous fat will appear uniform thickening. Third, in terms of treatment, ascites is a variety of reasons for the lack of albumin synthesis, the most common clinical cirrhosis or a variety of malignant tumors, the need for symptomatic or even surgical treatment for the primary cause. Obesity is mainly fat deposition caused by excess nutrition, so it can usually be reversed mainly by controlling the energy intake and strengthening physical exercise.