Valsartan belongs to the angiotensin II receptor antagonist (ARB), which can be used in combination with calcium channel blockers (CCB) and diuretics for better effect. ARB can be combined with dihydropyridine CCB such as nifedipine, diuretics such as hydrochlorothiazide to lower blood pressure effect is significant.ARB therapeutic dosage window is wider, the effect of the onset of action is slow but long-lasting and smooth. ARB is contraindicated in hyperkalemia, pregnant women, bilateral renal artery stenosis, especially for patients with diabetes mellitus, myocardial infarction, adverse effects mainly headache, dizziness, fatigue and so on. The drug combination application of hypertension should be individualized so you should go to the hospital in time and select the drug combination that is suitable for you under the guidance of professional doctors.