The dangers of bile duct stones include causing cholangitis, pancreatitis, liver damage, bile duct cancer, which can be life-threatening. 1. Cholangitis: bile duct stones will cause obstruction of bile duct, which can cause acute cholangitis when secondary bacterial infection occurs. If the inflammation worsens, it will cause purulent change of bile duct, leading to acute obstructive purulent cholangitis, which will jeopardize patients’ lives. 2. Pancreatitis: If the bile duct stone is stuck in the lower end of the common bile duct, it will cause the bile to flow back to the pancreas, resulting in acute pancreatitis, which will jeopardize the patient’s life. 3. Liver damage: If the inflammation caused by bile duct blockage involves liver tissue, it may cause liver abscess, liver fibrosis, cirrhosis, liver atrophy and other conditions, resulting in liver damage. 3. Cholangiocarcinoma: If bile duct stones stimulate the bile duct repeatedly and for a long time, it may lead to cancerous transformation of bile duct and cause cholangiocarcinoma. Therefore, once diagnosed with bile duct stones, timely and standardized treatment should be carried out to avoid delay.