There are many causes of high phosphocreatine kinase, common causes include malnutrition, of which people with pseudohypertrophic myotonic dystrophy are the most likely to have it. For this group, they should eat foods high in protein and vitamins, such as lean meat, milk, fish, and meat. In addition, a lot of exercise, such as long-distance strenuous cycling, skiing and marathon running can lead to a high level of creatine kinase. In this case, first of all, the amount of exercise should be appropriate, and before exercise should also do the corresponding auxiliary activities to avoid injury. In addition, pathological conditions are mainly seen in patients with hepatitis B infection and patients with acute myocardial infarction. For patients with hepatitis B infection, the first step should be to determine whether the viral load is too high. Patients with high viral load should be given timely antiviral treatment, such as oral entecavir and adefovir, as well as liver protection treatment to actively reduce transaminases and bilirubin. Patients with acute myocardial infarction should be given high priority, as this condition may cause death at any time. First of all, anticoagulation, blood circulation improvement, blood pressure control and other treatments should be given, close monitoring of vital signs, and if possible, coronary intervention and stent placement if necessary.