Vulvar squamous cell carcinoma generally refers to vulvar squamous cell carcinoma, which is mainly treated by surgery, supplemented by radiotherapy and chemotherapy. Patients with vulvar squamous cell carcinoma mainly have vulvar itching, nodular, cauliflower-like or ulcerated swellings on the vulva, and when the swellings are combined with infections or the disease has progressed to the advanced stage, symptoms of pain, oozing and bleeding will appear. Cancer cells may also metastasize, and if they metastasize to the inguinal lymph nodes, hard texture and inactive enlarged lymph nodes can be touched in the inguinal area. The treatment of patients is mainly based on surgical resection, such as extensive vulvectomy, enlarged vulvectomy, and inguinal lymph node dissection. For patients who cannot undergo surgery, or who have a high risk of recurrence, radiotherapy and chemotherapy are needed to control the progression of the disease. Some patients with advanced disease may need radiotherapy before surgery to create conditions for surgery. It is recommended that patients actively consult their doctors and choose the appropriate treatment according to their condition.