Diarrhea caused by bacterial infection can be treated with norfloxacin. If the diarrhea is caused by Escherichia coli, Shigella spp. infection, Norfloxacin 0.1g dosage form can be taken twice a day, 3~4 capsules each time. Norfloxacin has a broad-spectrum antibacterial effect, especially for aerobic gram-negative bacilli with high antibacterial activity, as well as Enterobacter cloacae, Klebsiella spp., Aspergillus spp., Salmonella spp. and Shigella spp. have good antibacterial effects. It can be used for diarrhea caused by the above bacteria. Adverse reactions such as abdominal discomfort or pain, diarrhea, and nausea may occur after use. Breastfeeding should be discontinued when applied to breastfeeding women. The use of this drug is prohibited for those who are allergic to this drug or the components of the formula, patients under 18 years of age, pregnant women. The specific dosage and usage of the above medicines should follow the doctor’s instructions and should not be used on its own to avoid adverse reactions.