Pressing pain is not a typical symptom of duodenal ulcer. However, duodenal ulcers may present with pressure pain, and in addition to pressure pain, periodic, rhythmic epigastric pain may occur, accompanied by symptoms such as heartburn and acid reflux. Duodenal ulcer patients with pain on pressure, due to the pressure will touch the ulcer area, thus causing the phenomenon of pain, if the ulcer surface bleeding phenomenon, will also make it have pain. Duodenal ulcer pain is characterized by pain in the empty stomach, after eating some relief, the nature of the pain can be dull pain, burning pain, swelling, severe pain, some patients do not have obvious abdominal pain. If patients do not take effective treatment measures, it is easy to lead to perforation or even cancer. Duodenal ulcer patients need to go to a regular hospital, under the guidance of physicians to choose reasonable drugs and methods of treatment, they can not just indiscriminate use of drugs.