Small blisters on the soles of the feet (i.e., “blisters”) with itching may be caused by ringworm of the feet, eczema, sweat herpes and other diseases. 1. Tinea pedis: This disease is mainly caused by fungal infections of the skin on the feet, which can lead to small blisters on the soles of the feet, itching, and may be accompanied by erosion of the skin in the affected area, flaking and other symptoms. 2. Eczema: the cause of the disease is unknown, may be related to genetic, environmental, infection, allergies and other factors, when eczema on the feet, may lead to the soles of the feet erythema, papules, pimples, with itching, may also appear oozing, erosion and other symptoms. 3. Sweat herpes: the etiology is not yet clear, and may be related to psychosomatic factors, heredity, infection, and allergies. It occurs on the hands and feet, causing small blisters on the soles of the feet, itching, and may be accompanied by symptoms such as flaking and pain in the affected area. Small blisters on the soles of the feet and itchy may also be caused by other diseases, it is recommended that patients go to a regular hospital as soon as possible to confirm the diagnosis, and then give targeted treatment.