Although there are treatments for Tourette’s, they are not completely curable. Tourette’s usually starts in childhood and may decrease in frequency and severity by the time the patient reaches adolescence, and in some cases the symptoms disappear completely during adolescence, but most patients have symptoms that persist into adulthood. The symptoms of Tourette’s syndrome then manifest as facial twitching, as well as shrugging, blinking, pouting, or making abnormal noises, with some strange screaming sounds that are not under one’s control. The disease is associated with hypersensitivity to dopamine in the basal nucleus of the brain and is often triggered when the patient is emotionally stressed, or under stress.