The disadvantages of autologous fat facial filler are: the possibility of secondary surgery, localized skin unevenness, and limited applicability. 1. Secondary surgery: the fat filled after autologous fat facial filler usually has a certain absorption rate, the degree of absorption is affected by many factors, there is a single filler can not achieve the desired results, there is a possibility of secondary surgery. 2. Uneven skin: If the level and amount of fat filling are not uniform during the operation, there may be localized uneven skin, which affects the aesthetics. 3. Limited applicability: Autologous fat facial filler requires sufficient subcutaneous fat volume, if the patient is thin and cannot provide the required fat, he/she is not suitable for this surgery. In addition to the above, autologous lipofilling may cause bleeding, infection, hard lumps under the skin, or fat liquefaction. It is recommended to go to a regular medical institution for autologous fat facial filler, find an experienced doctor to operate, and make relevant preparations before the operation, so as to improve the safety and the effect will also be better.