It is not normal that there is always one side of the nose that is not ventilated. It may be caused by deviated nasal septum, nasal mass, etc. It is recommended to treat it actively. 1. Deviated nasal septum: when trauma or congenital developmental abnormalities, resulting in a deviated nasal septum, which can lead to a narrow airway on the deviated side of the inability to ventilate, and in severe cases, need to undergo a deviated nasal septum corrective surgery. 2. Nasal mass: if there are polyps, inverted papilloma, nasal malignant tumor, etc. formed in one side of the nasal cavity, it will cause the narrowing of the airway on the affected side, which can not be cured by drugs, and need to take surgical excision treatment, and if necessary, combined with chemotherapy and radiotherapy. It is recommended that patients with unilateral nasal stomata should go to the hospital in time, and follow the doctor’s instructions for medication and treatment after the diagnosis is clear.