Generally, cold and flu medicines should not be taken in the early stages of pregnancy, as they can easily lead to miscarriage or cause fetal malformations as well as other adverse reactions. Cold medicine is a generalized term, in fact, most of them refer to cold medicines in compound preparations, such as common pseudoephedrine, phenmetrazine, compound aminophenolamine, etc. These medicines have a complex composition, including both non-steroidal anti-inflammatory drugs, antihistamines, cough suppressants and antivirals, etc., and are of a lower grade of medicines used in pregnancy, with high risks and potential side effects, and generally cannot be used in pregnancy. There are also some cold and flu medicines that are proprietary Chinese medicines or a mixture of Chinese and Western medicines, most of which contain heat-clearing and detoxifying Chinese medicines, such as honeysuckle and panax quinquefolium, etc. However, the safety of these Chinese medicines is unknown, and they have unpredictable risks, so they are also unsuitable for use during pregnancy. Therefore, cold and flu medicines should not be taken in the early stages of pregnancy, not to mention that most colds are self-limiting.