The HPV vaccine is usually not given early, but can be delayed slightly. In the course of the study, it was found that postponing the vaccine did not have a significant impact on the immune response, but early vaccination may not have enough time to immunize and affect the effectiveness of the vaccine. The vaccines are 2-valent, 4-valent, and 9-valent, and all three vaccines can be postponed a little bit, but not in advance. 2 valent vaccination protocol is 0-1-6, i.e., after 1 shot, the 2nd shot will be given 1 month later, and the 3rd shot will be given around 6 months, i.e., all 3 shots will be given around 6 months and 6 months. If you push back, for example, the first shot to the date of vaccination, it does not matter if you push back a few days, or if you push back the third shot to 6 months, it does not matter too much. The same applies to the 4-valent vaccine, which is a 0-2-6 regimen, and the 9-valent vaccine, which is also a 0-2-6 regimen, where the second dose is given in the second month and the third in the sixth month. If the vaccination is postponed for reasons such as a cold or fever, the vaccination cannot be given until the cold and fever have completely recovered. If you have a menstrual period, you can usually have the vaccination normally, except that some people may feel very uncomfortable after menstruation and have generalized aches and pains or chills, so if you are very uncomfortable during your menstrual period, you can postpone the vaccination. In general, HPV vaccine can be given on time, or it can be postponed slightly, but not in advance.