Obesity is a common metabolic abnormality, long-term obesity can cause a variety of diseases, mainly the following points, one, obesity can cause hypertension, hyperlipidemia. Second, long-term obesity can lead to insulin resistance, the body to maintain normal blood sugar will promote insulin secretion. Long-term insulin resistance will increase the burden of pancreatic β-cell function, and even the occurrence of diabetes. Third, cardiovascular disease, obesity, hypertension, hyperglycemia, hyperlipidemia, etc., can aggravate the occurrence and development of atherosclerosis, and even coronary heart disease, cerebral infarction, etc. Fourth, obesity can cause the increase of uric acid, leading to hyperuricemia, or even uric acid nephropathy or obesity-related kidney damage, etc. Fifth, long-term obesity will increase the burden of joints, aggravate joint degeneration, the formation of osteoarthrosis. Sixth, obesity will lead to restricted thoracic activity, affecting respiratory function. Sixth, obesity will lead to sleep apnea syndrome at night, resulting in chronic hypoxic damage to the brain and the body.