Prednisone is prednisone acetate, the difference between dexamethasone and prednisone acetate mainly lies in the adverse drug reactions and effect time. 1. Adverse drug reactions: Prednisone acetate may cause Cushing’s syndrome, diabetes, etc., in addition to the risk of stillbirth, teratology, etc., so this drug is prohibited for pregnant women to take, and dexamethasone may lead to gastrointestinal reactions, endocrine abnormalities, endocrine system abnormalities, so can not be given to diabetic patients to take. 2. Effect time: Prednisone acetate is an intermediate-acting agent with a half-life of 60 minutes in the blood, while dexamethasone is a long-acting agent with a half-life of 190 minutes in the blood, and dexamethasone’s anti-allergic and anti-inflammatory effects are stronger than those of prednisone, and the effects are more rapid and long-lasting, commonly used in acute patients, relatively speaking, prednisone acetate is more suitable for long-term treatment. Drugs need to be used under the guidance of a physician, it is recommended that patients who need to take dexamethasone or prednisone acetate to the relevant departments of regular hospitals for consultation.