Depending on the cause, medial knee pain after running should be relieved by general treatment, medication, physical therapy and surgery. It may be caused by strain injury, medial meniscus injury, articular cartilage injury and so on. 1. Strain: Excessive knee movement caused by running and other activities can cause strain on the medial soft tissues, resulting in chronic inflammatory lesions and pain. You need to pay attention to rest, can be carried out by professionals local massage, acupuncture, massage and other physical therapy, but also oral ibuprofen and other pain medication. 2. Medial meniscus injury: If there is basic degeneration of meniscus and other soft tissues, meniscus injury is easy to occur after running and other sports, which can be manifested as pain in the medial side of the knee joint. It is necessary to reduce the activities of the knee joint and rest with more braking. Anti-inflammatory and analgesic drugs such as Celecoxib can be taken orally, and physical therapy such as hot compresses and grilled electricity can also be carried out. Conservative treatment is ineffective, if necessary, surgery to repair or remove the damaged meniscus. 3. Articular cartilage injury: joint cartilage of the elderly often occurs serious degenerative changes, when running sports can lead to articular cartilage damage aggravated, the medial pain symptoms. It is necessary to pay attention to the knee joint warmth and braking, oral ibuprofen and other analgesic drugs, but also can be injected into the joint cavity of sodium vitrate in the nutrition of articular cartilage treatment, the serious injury can be feasible for knee arthroplasty and other surgical treatments. Running knee pain can also be caused by many diseases, such as trauma, lumbar disc herniation, etc., if rest does not relieve, it is recommended to consult a doctor in a timely manner, improve the examination to clarify the cause of the disease, comply with the doctor’s instructions for targeted treatment, do not use their own medication, so as not to delay the condition.