Betalock (i.e., metoprolol tartrate) and nifedipine can usually be taken at the same time, commonly used in the treatment of hypertension, the specific use of drugs need to follow the doctor’s instructions. 1. Metoprolol tartrate is the first line of antihypertensive drugs in clinical practice. In addition to lowering blood pressure, it also slows down the patient’s heart rate and inhibits sympathetic excitability. Common adverse reactions include nausea, stomach pain, etc. This drug is prohibited for those who are allergic to it. 2. Nifedipine: Nifedipine is a calcium channel blocker, which has the effect of weakening myocardial contractility, and it is also a first-line antihypertensive drug in the clinic. Some patients, after taking nifedipine, may have reflex rapid heartbeat, lower limb edema, etc., which is prohibited for those who are allergic to this drug. The above drugs can be used in combination when the effect of single drug treatment is not good. If the patient also has heart failure, it is not recommended to take the two drugs at the same time, because both drugs have negative inotropic effects, which will aggravate the symptoms of heart failure. Regardless of which drug is used to lower blood pressure, it should be done under the guidance of a doctor to avoid delaying the treatment of the disease.