Drinking mulberry in wine is effective for insomnia caused by yin and blood deficiency, but it is generally recommended that mulberry be used in decoction for better results. Mulberry is sweet, sour and cold in nature, it is a traditional Chinese medicine, it has the effect of tonifying blood, nourishing yin, generating fluids and moistening dryness; it is used for treating yin deficiency of liver and kidney (deficiency of yin in liver and kidney), dizziness, tinnitus, palpitations (rapid heartbeat, often accompanied by panic), insomnia, premature whitening of the beard and hair, thirst due to injury of fluids, thirst due to internal heat (internal fever accompanied by symptoms such as overeating, excessive drinking, excessive urination, etc.), intestinal parchedness, and constipation. Mulberry has some therapeutic effect on insomnia caused by deficiency of Yin and Blood, but Chinese medicine mainly works by decoction, while wine is a kind of beverage, so drinking wine may affect the release of active ingredients, which may affect the therapeutic effect. The adverse reactions and contraindications of mulberry are not clear. Those who are allergic to alcohol should be prohibited from taking medicinal wine. If medication is needed, it is recommended to use it under the guidance of a Chinese medicine practitioner, unauthorized use of medication may cause adverse consequences.