Bile reflux generally has no effect on life expectancy and may affect survival time if complicated by other diseases. Normal surgery, such as gastrectomy, cholecystectomy, postoperative gastrointestinal peristalsis ability is insufficient, can not be excess bile normally discharged, and thus the duodenum to the stomach influx, may cause reflux gastritis, esophagitis, can take omeprazole, ursodeoxycholic acid capsules for treatment, usually does not affect life expectancy. If the complication of serious diseases such as gastric cancer, according to the severity of malignant tumor disease, it will have different degrees of impact on the survival time, should be timely to the hospital for early detection and treatment. Therefore, patients with bile reflux should pay attention to the need to reasonably regulate their diets, focus on light, avoid overeating, eat less and more often, and those with serious conditions should be supplemented with medication or timely consultation.