Gallstone disease occurs in the following groups of people: first, lazy people, such as those who like to be quiet and less active, because these people have less exercise and physical labor, so the contraction force of the gallbladder muscle is reduced, which can cause obstacles to bile evacuation, causing gallstone disease. Secondly, some obese people, such as those who usually love to eat high fat, high sugar, high cholesterol drinks or snacks, it is an important basis for gallstones. Third, people who do not eat breakfast, now many people do not eat breakfast, long-term skipping breakfast will increase the concentration of bile, thus promoting the occurrence of gallstone disease, so we must insist on eating breakfast. The fourth, some patients with cirrhosis of the liver due to metabolic disorders will cause the occurrence of cholelithiasis. Fifth, there are also some genetic factors, such as parents, grandparents have gallstone disease, have this genetic predisposition, may also occur gallstone disease.