How long does it take for aminotransferase 700u/L to come down depends on the cause of the disease, the progress of the disease and the treatment, and can not be generalized, generally can be improved within 1-3 months after active treatment. Transaminase is an important indicator of liver function, mainly including alanine aminotransferase and glutamic aminotransferase, the normal value is 0-40U/L, is the liver as a chemical factory in the normal operation of the essential catalyst, when the liver cells are significantly damaged, the integrity of the cell membrane will be damaged, the transaminase will be released into the bloodstream, in particular, glutamic aminotransferase is elevated, usually indicates that the liver has a more serious injury. Injury. This is usually seen in a variety of liver diseases, such as viral hepatitis, fatty liver, alcoholic liver, autoimmune hepatitis, and injury from drugs and toxins. If it is caused by drugs, poisons, alcohol and other reasons, it can usually be reduced to normal in about 4 weeks after removing the cause of the disease; damage caused by viral hepatitis, especially hepatitis B virus infection, requires antiviral and hepatoprotective treatment such as entecavir, and most of them can be improved in 1-3 months. Once the transaminases increase significantly, we must pay great attention to it and standardize the treatment under the guidance of specialists in order to prevent further deterioration of the condition and lead to liver failure and various complications that may endanger the life; at the same time, we should pay attention to adjusting the living habits, combining work and rest, quitting smoking and drinking and avoiding staying up late at night.