Morpholine is a blocker of peripheral dopamine receptors, which generally acts on the gastrointestinal wall to increase lower esophageal sphincter tone, prevent gastroesophageal reflux, enhance gastric motility, and promote gastrointestinal emptying. It is commonly used clinically for functional dyspepsia, or organic gastrointestinal disease with nausea, vomiting, epigastric distention and other symptoms, and is more effective. However, there are contraindications. It should not be taken orally if the patient is allergic to the ingredients of domperidone, or if there is gastrointestinal bleeding, intestinal obstruction or gastrointestinal perforation. If the patient normally takes clarithromycin or heart drugs, such as amiodarone and other class of drugs, the combination should not be applied, this must be noted.