Patients sleep with sore legs, there are two reasons to consider this situation, including calcium deficiency, muscle strain, as follows: First, calcium deficiency: the most common is calcium deficiency, calcium ions can inhibit the excitability of the neuromuscular junction, when calcium deficiency neuromuscular excitability will increase, often manifested as calf spasms, as well as calf twitching, pain, the most obvious time for this symptom is at night, there will be calf belly cramps . Second, muscle strain: consider calf muscle strain, is due to a large number of recent sports or excessive super compound sports activities, causing chronic strain on the calf muscle fibers, will cause lactic acid accumulation, will also be manifested as calf soreness, in the quiet state at night, soreness will be particularly obvious.