The difference between confirmed and asymptomatic infections is the presence or absence of definite clinical manifestations. A confirmed infection has a clear set of clinical manifestations of the disease in which the pathogen is infected, whereas an asymptomatic infection has no clinical manifestations. In a confirmed infection, the immune system loses the battle against the virus and the virus invades the body, leading to a variety of associated clinical manifestations. An asymptomatic infection is one in which the immune system has not yet failed in its fight against the virus, so an asymptomatic infection can either regress to a confirmed diagnosis or be cured outright. Both confirmed and asymptomatic infections are contagious and therefore require isolation. The difference is that a confirmed person is isolated for treatment, while an asymptomatic infected person is isolated for observation and further judgment based on changes in condition.