Acne on the mouth can be treated with general therapy, topical medication, phototherapy, and adjunctive therapy. 1. General treatment: you can use the appropriate cleansing products to remove excess oil on the skin surface and bacterial compounds, in addition to limiting milk intake and high glycemic index food intake, avoid staying up all night, and keep the bowels open. 2. Topical medication: Vitamin A drugs can be used, such as first-generation isotretinoin and third-generation vitamin A cream; antibiotics can be used for anti-infective treatment, such as fusidic acid cream, erythromycin ointment, clindamycin and other topical preparations, but also the use of salicylic acid cream and sulfur lotion can be used to inhibit the growth of the bacterium Pseudomonas aeruginosa. 3. Phototherapy: LED blue light or red light can be used to treat mild to moderate lesions. 4. Adjuvant treatment: Acne squeezer can be used to squeeze out the contents of acne, in addition to the use of chemical peeling therapy, common peeling agents are fruit acid, salicylic acid, trichloroacetic acid and so on. All of the above drugs must be used under the guidance of a doctor.