In the clinical blood pressure only high pressure is called simple systolic hypertension, usually need to take antihypertensive drugs to lower blood pressure, which to calcium channel blockers to reduce high pressure effect is better. Calcium channel blockers can be divided into dihydropyridines and non-dihydropyridines. The former is represented by nifedipine and amlodipine, while the latter has verapamil and diltiazem. These antihypertensive drugs have a rapid onset of action, relatively strong antihypertensive efficacy and magnitude, and can significantly enhance the antihypertensive effect when used in combination with other types of antihypertensive drugs. Calcium channel blockers are particularly suitable for hypertension in the elderly, have no significant effect on blood lipids, blood glucose, etc., and can be used in patients with combined diabetes mellitus and coronary heart disease. Its main adverse effects include increased reflex sympathetic activity, which can cause increased heart rate, facial flushing, lower limb edema. In addition, simple systolic hypertension can also be based on the individual situation, selective use of diuretics, such as hydrochlorothiazide; β-receptor antagonists, such as propranolol; can also take angiotensin-converting enzyme inhibitors, such as captopril; angiotensin receptor antagonists, such as valsartan. If simple systolic hypertension occurs, you should go to the hospital in time and choose drugs under the guidance of a specialist.