Infection with the novel coronavirus produces an inflammatory response to the entire respiratory system, with cough and fever. When the inflammatory lesions invade the lung parenchyma, especially when the lesions are in the outer bands of the lungs, near the pleura, a pleural reaction often occurs. In some patients, the pleural reaction is severe and may be characterized by chest pain, but chest pain is not a mandatory symptom of novel coronavirus pneumonia. However, chest pain is not a mandatory symptom of novel coronavirus pneumonia. In some patients, the inflammation has invaded the pleura, and the patient may even develop hydrothorax. Source: Dr. Yurai