Is a naïve granulocyte percentage of 1.1 serious?

A naïve granulocyte percentage of 1.1 is not serious and is within the normal range. Among the bone marrow cytology programs, the percentage of naïve granulocytes, which is important for the diagnosis of hematologic diseases, includes the percentage of promyelocytes and the percentage of primitive granulocytes, whose normal value ranges from 0.4% to 3.9% and from 0 to 1.8%, respectively. Therefore, a naïve granulocyte percentage of 1.1% is within the normal range and therefore not serious. Elevated naïve granulocyte percentage can be seen in human infections (e.g. Streptococcus pneumoniae, boils or carbuncles, etc.), which are accompanied by leftward shifting of granulocyte nuclei, and elevated leukocytes and neutrophils in peripheral blood tests, often accompanied by elevated inflammatory markers, such as C-reactive protein and procalcitonin, etc., which can be restored to normal after anti-inflammatory treatments. Increased percentage of naïve granulocytes can also be seen in acute leukemia, chronic granulocytic leukemia, myelodysplastic syndromes and other hematologic malignant diseases, such patients with markedly elevated primitive granulocytes, but often do not have the manifestation of left shift of the nucleus, and need to be combined with a bone marrow biopsy, flow cytometry, bone marrow biopsy and other tests to clarify the diagnosis.