Scrotal eczema is divided into two types: moist and dry. Scrotal edema, erosion, oozing and hypertrophy are the main clinical symptoms of moist scrotal eczema, while dry eczema mainly manifests as scrotal skin thickening, deep wrinkles, scaling and mossy changes. Scrotal eczema has a long course and is prone to recurrence, with itching being the most typical feature. When the exudate and vesicles are obvious, usually first wet compress with saline or boric acid water to clean the trauma, after which topical creams can be applied: 1. Non-hormonal creams: non-steroidal anti-inflammatory drugs such as butalbital hydroxy acid cream, antibiotics such as tacrolimus cream and pimecrolimus cream. Pimecrolimus cream has an inhibitory effect on a variety of interleukins and interferons, and inhibits mast cells and eosinophils from producing inflammatory factors, with anti-itch, anti-inflammatory, immunomodulatory effects, high affinity for the skin, suitable for direct application treatment; 2, hormonal creams: such as hydrocortisone butyrate cream, mometasone furoate cream, etc., has a strong anti-inflammatory effect, long-term application should be considered adverse reactions, should follow the 3, compound preparations: such as compound dexamethasone acetate cream, trimethoprim econazole cream, etc.; 4, moisturizers, keratolytic agents: more suitable for dry scrotal eczema, such as urea ointment, salicylic acid ointment, etc.. When the inflammatory reaction is severe, the doctor may use antihistamines with the treatment, such as loratadine and cetirizine, which have anti-itch and anti-inflammatory effects. In case of complicated bacterial infection, antibiotics such as penicillin and cephalosporin will also be added.