The scrotal area of men is hidden, the skin is delicate, and the area is not ventilated, plus the hot weather in Wuhan in summer, sweat impregnated with humidity, often appear red spots, papules, because of intense itching, repeated scratching, and even erosion, oozing. The diagnosis of “scrotal eczema” is often made at the hospital. Most scrotal eczema can be improved by paying attention to local hygiene and changing your lifestyle. It is recommended that the scrotal skin folds be completely cleaned in the shower and partially dried before wearing underwear, and it is best to wash and change underwear daily. For those who are prone to sweating, you can sprinkle a little baby powder on the affected area to absorb sweat. You should eat more fresh fruits and vegetables, fill in vitamin B at the right time, avoid spicy and other stimulating foods, and stop drinking. The actual fact is that you can find a lot of people who are not able to get the best out of your own home. This is the time to go to the hospital and have a histopathological examination. This is because it may no longer be a simple “scrotal eczema”, but may be “extramammary Paget’s disease”. Paget’s disease, also known as “eczema-like carcinoma outside the breast”, is usually seen in people over 50 years of age, and is usually found in the perineum, where sweat glands are abundant. Currently, the main treatment is surgical excision, which generally requires excision along the outer 50px of the lesion margin. Therefore early detection and small excision can reduce the difficulty of surgery. Recurrence is still possible after surgery, and can be reduced by postoperative treatment with photodynamic therapy or topical imiquimod ointment.