Adverse reactions to piperacillin sodium tazobactam sodium include systemic allergic reactions, gastrointestinal reactions, neurologic reactions, hematologic reactions and others. 1. Systemic allergic reactions: itching, rash, fever, exfoliative dermatitis, urticaria, etc. may occur, and anaphylaxis may occur in severe cases. 2. Gastrointestinal reactions: nausea, vomiting, abdominal pain, diarrhea and other symptoms may occur. 3. Nervous system reaction: twitching and numbness of limbs may occur. 4. Hematologic system: It leads to reduction of granulocytes, leukocytes, platelets and so on. 5. Other: when the drug penetrates into the subcutaneous, local pain, edema, etc. are likely to occur, and phlebitis may occur in severe cases. There may also be liver and kidney function damage. Drugs need to be used under the guidance of a doctor, when there are obvious adverse reactions, you need to stop the drug in time and consult a doctor.