Causes and treatment of high uric acid

There are two reasons for high uric acid: first, excessive intake of uric acid from exogenous sources. Secondly, insufficient excretion of endogenous uric acid. Excessive uric acid intake is mainly caused by high purine diet. Excessive intake of high purine food can easily lead to a significant increase in blood uric acid, such as seafood, various kinds of alcohol, animal offal, some beans and so on. All of these are high in purines, and excessive intake will easily lead to elevated blood uric acid. Insufficient uric acid excretion is often due to renal tubular function, if there is chronic kidney disease such as glomerulonephritis, nephrotic syndrome, chronic pyelonephritis, these will lead to a decrease in the ability of the kidneys to excrete uric acid. The treatment includes both dietary modification and oral medication. The diet should pay attention to the high purine foods mentioned earlier, and must also be strictly controlled. Medications such as allopurinol and benzbromarone are commonly used to reduce the synthesis of uric acid from purines in the body or to promote the excretion of uric acid in the body, which can lead to a decrease in uric acid.