Itchy skin after drinking alcohol is a symptom of alcohol allergy. Most of the time, alcohol allergy is caused by the lack of ethanol dehydrogenase or acetaldehyde dehydrogenase in the liver, which causes alcohol, or ethanol, to enter the body and not be metabolized quickly, resulting in the accumulation of ethanol or acetaldehyde in the body and causing an allergic condition. In mild cases, patients may have flushing, itchy skin or hives, and in severe cases, it may even lead to anaphylactic shock such as chest tightness and difficulty breathing. Therefore, patients with post-drinking itchy skin should try to reduce alcohol consumption and drink more water once itchy skin occurs after drinking to help metabolize ethanol and discharge it. In addition, you can use topical ointment or salve to stop itching, and you can take oral anti-allergy medication as well as vitamin C to help treat it.