Enteric-coated aspirin refers to the enteric-coated preparation of aspirin, and the best time to take it is early in the morning before breakfast to better utilize the efficacy of aspirin. Aspirin enteric-coated preparations include enteric-coated capsules, enteric-coated tablets, etc. It is commonly used for anti-inflammatory, analgesic, antipyretic, and can be used to prevent thrombosis. It is generally recommended to take it in the morning before meals, because taking it on an empty stomach can reduce the residence time of aspirin in the stomach, reduce the influence of gastric juice, and better fulfill the efficacy of the drug, thus patients are not recommended to take it after meals. Common adverse reactions to enteric formulations of aspirin include nausea, vomiting, abdominal pain, and tinnitus. The drug is contraindicated in those who are allergic to aspirin, those with active peptic ulcers and bleeding, those with severe heart failure, those with severe hepatic or renal failure, hemophilia or thrombocytopenia. The use of aspirin enteric-coated preparations should be under the guidance of medical professionals.