Discomfort in the right lower abdomen may be caused by chronic appendicitis, salpingitis, Crohn’s disease and other causes. 1. Chronic appendicitis: chronic appendicitis is a chronic inflammatory lesion of the appendix left after the acute inflammation of the appendix subsides, mainly manifested as right lower abdominal pain, some patients are also accompanied by loss of appetite, abdominal distension, postprandial discomfort, constipation, diarrhea and other symptoms. 2. Tubulitis: Tubulitis is an inflammatory disease that occurs in the fallopian tube, mainly manifested as pain in the right lower abdomen, fever, increased secretion and other symptoms, when the patient’s right fallopian tube inflammation, the patient may experience discomfort in the right lower abdomen and other symptoms. 3. Crohn’s disease: Crohn’s disease is a chronic inflammatory granulomatous disease, most commonly found in the terminal ileum and adjacent colon, mainly abdominal pain, diarrhea, weight loss as the clinical manifestations, the patient’s right lower abdomen discomfort may be caused by Crohn’s disease. It is recommended that patients seek timely medical examination, clear causes for targeted treatment, pay attention to rest in life, avoid strenuous exercise or excessive labor.