It is not good to apply safflower oil immediately after spraining the foot, because after spraining there will be obvious bleeding inside, resulting in swelling of the joints, and safflower oil has a very good effect of activating blood circulation, removing blood stasis and relieving pain. The use of safflower oil at this time will aggravate the internal bleeding and increase the swelling. Only after 48 hours after the sprain, the whole bleeding situation has completely stopped before using safflower oil, can make the original bleeding situation get good subside, help relieve pain and swelling problems. Within 24 hours of the sprain, only ice packs should be used, as the principle of heat expansion and cold contraction can reduce the bleeding situation, thus relieving the pain and swelling. The timing of safflower oil after a sprain must be well-timed, otherwise it can sometimes be counterproductive.