Scrotal redness and swelling may be caused by epididymitis, scrotal eczema, varicocele, etc. Different treatments need to be used for different causes, including medications such as levofloxacin hydrochloride tablets, fusidic acid cream, sodium heptadecanoate tablets, and so on. 1. Epididymitis: Epididymitis is caused by the retrograde invasion of the epididymis due to the entry of pathogenic bacteria into the vas deferens, which can lead to redness and swelling of the scrotum. You can use levofloxacin hydrochloride tablets, azithromycin dispersible tablets and other medications as prescribed by the doctor. 2. Scrotal eczema: Scrotal eczema occurs due to inattention to hygiene, long-term mental stress, allergies or ill-fitting underwear, resulting in scrotal redness, swelling, itching and pain. You can use cetirizine tablets, fusidic acid cream or glycerine lotion and other drugs to treat it. 3. Varicose veins: As patients suffer from varicose veins of the spermatic cord, the veins are tortuous in the form of masses or nodules, which may lead to redness and swelling of the scrotum, and patients can be treated with medicines such as hepaticoside sodium tablets. Patients with scrotal redness and swelling should go to the hospital in a timely manner, clear the cause of the disease and follow the doctor’s instructions for treatment, do not blindly use drugs.