Smoking has the potential to raise blood pressure. Common risk factors for hypertension include hereditary factors, age, and controllable factors, including diets high in sodium and low in potassium, sedentary lifestyle, low physical labor, obesity, smoking, alcohol abuse, and mental stress. Smoking tends to damage the endothelial cells of blood vessels, which reduces the elasticity of blood vessels and increases blood pressure. Smoking also causes vasospasm and increased sympathetic excitability, which leads to faster heart rate and higher blood pressure. In addition, smoking can induce related diseases, resulting in ischemia, hypoxia, and reflexive increase in blood pressure. Therefore, for patients with high blood pressure, therapeutic lifestyle improvement is recommended, including low-salt and low-fat diets, smoking cessation and alcohol restriction, appropriate exercise, maintaining an optimistic and positive attitude towards life, supplemented by 24-hour smooth antihypertensive medication, in order to control the blood pressure and minimize the consequential damage to target organs.