High-grade uroepithelial carcinoma of the bladder is a poorly differentiated and highly malignant bladder cancer originating from the uroepithelium, which requires aggressive treatment such as surgery. According to different sources, bladder cancer can be classified into various types, including uroepithelial carcinoma, squamous carcinoma, adenocarcinoma, malignant tumor of umbilical ureter, malignant tumor of Müllerian duct, and mesenchymal tumor. Uroepithelial carcinoma, a tumor derived from migratory cells, is the most common subtype and accounts for the majority of bladder cancers. Uroepithelial tumors are subdivided into three types: low malignant potential papillary uroepithelial tumors, low-grade and high-grade papillary uroepithelial carcinoma, and high-grade papillary uroepithelial carcinoma, which has a relatively high risk of recurrence, metastasis, and tissue invasion, and a greater degree of malignancy. However, it should be noted that the prognosis of high-grade tumors is not necessarily bad. If the tumor can be detected at an early stage, surgically removed and treated with radiotherapy and chemotherapy, there is also a better prognosis. If bladder cancer is suspected, it is recommended to go to the hospital for consultation.