Toe pain may be due to shoe discomfort, trauma, gout, lumbar disc herniation, vascular embolism and diabetic complications. 1. Shoe discomfort: Shoes that are too short or too crowded may lead to squeezing of the patient’s toe area, thus causing toe pain to occur. 2. Trauma: the toes are hit or extruded, which may cause soft tissue injury or fracture of the foot, and the patient will also suffer from localized edema and pain, which may affect the joint activities when the symptoms are serious. 3. Gout: gout is due to the body due to high uric acid blood accumulation caused by multiple or single joint pain, this disease will cause patients with localized joint fever, redness, swelling, pain and other symptoms. The pain caused by gout is usually more intense, and sometimes activities will be limited. 4. Lumbar disc herniation: Lumbar disc herniation can cause radiating pain in the lower limbs because the nucleus pulposus tissue compresses the nerve root, which can radiate to the toe area. Toe pain occurs. 5. Vascular embolism: when there is embolism in the blood vessels of the lower limbs, such as venous thrombosis and arteritis, the blood circulation in the distal part of the foot is impaired, and the pain can be caused by poor blood circulation in the toes. 6. Diabetic complications: advanced diabetes can cause toe pain due to poor blood circulation, causing ischemia and hypoxia in the extremities, causing pins and needles pain. Toe pain can not be recovered for a short time, should be promptly to the hospital for examination and treatment.